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Phenomenon of “contact guidance“ on the surface with nano-micro-groove-like pattern and cell physiological effects

  • Review/Polymer Physics
  • Published:
Chinese Science Bulletin

Abstract

The topography of material surface has important influence on cell behavior and physiological functions. Groove-like pattern has drawn much attention among various patterns, due to the phenomenon of “contact guidance“ induced by this kind of topography. This review mainly focuses on “contact guidance“ formation as well as its influence on cell behavior and physiological effects. The possible mechanisms of “contact guidance” formation were discussed. The research trend and the potential applications were also suggested.

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Authors and Affiliations

  1. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan, 430070, China

    Feng Zhou, Lin Yuan, He Huang & Hong Chen

  2. School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070, China

    Feng Zhou, He Huang & Hong Chen

  3. Biomedical Materials Research Center, Wuhan University of Technology, Wuhan, 430070, China

    Lin Yuan

Authors
  1. Feng Zhou
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  2. Lin Yuan
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  3. He Huang
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  4. Hong Chen
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Correspondence to Hong Chen.

Additional information

Supported by the National Natural Science Foundation of China (Grant Nos. 90606013 and 20634030) and Key Grant Project of Chinese Ministry of Education (Grant No.107080)

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Zhou, F., Yuan, L., Huang, H. et al. Phenomenon of “contact guidance“ on the surface with nano-micro-groove-like pattern and cell physiological effects. Chin. Sci. Bull. 54, 3200–3205 (2009). https://doi.org/10.1007/s11434-009-0366-1

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  • DOI: https://doi.org/10.1007/s11434-009-0366-1

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